26 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... thiazide-sensitive sodium ... (renal potassium ... #nephrology #management
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... , Gitelman syndrom ... @priti899 #Hypokalemia ... Algorithm #causes #potassium ... #low #nephrology
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome • Urine ... krithicism #Gitelman ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Syndrome is a rare ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... , Gitelman syndrome ... #urine #potassium ... algorithm #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... • G-CSF • Hypokalemic ... • Refeeding syndrome ... Diagnosis #Algorithm #nephrology ... #low #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... , Gitelman's syndrome ... #hypokalemia ... algorithm #causes #nephrology ... #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... treated with IV potassium ... , Gitelman syndrome ... #differential #potassium ... #nephrology #low
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... , Gitelman's syndrome ... #Hypokalemia # ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... Fluids Shift potassium ... 90 minutes) • Sodium ... LouLectures #Hyperkalemia ... #nephrology