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diagnosis causes management acromegaly algorithm coagulation dic differential growthhormone hematology intravascular pediatrics pituitary shortstature
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... expansion (e.g. carpal ... #FeedbackLoop # ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... malignancy Pathophysiology ... pseudo-acromegaly, obesity, hypothyroidism ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Cushing's Disease • GH ... Dwarfism) • Hypothyroidism ... • Congenital Adrenal ... Panhypopituitarism Treatment ... Diagnosis #Algorithm #endocrinology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... protein C and S Pathophysiology ... Bleeding (64%) • Renal ... + Bleeding Treatment ... diagnosis #causes #treatment
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