16 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... Cardiovascular disease ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
paresthesias (carpal ... malignancy Pathophysiology ... pseudo-acromegaly, obesity, hypothyroidism ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Graves Hyperthyroidism - Diagnosis and Management Algorithm
Low TSH -> TSH-R-Ab+ -> Graves' Hyperthyroidism

doi: 10.1210/clinem/dgaa646

#Graves #Disease #Hyperthyroidism
Graves Hyperthyroidism ... dgaa646 #Graves #Disease ... #Hyperthyroidism ... Management #Algorithm #treatment ... #diagnosis #endocrinology
Graves' Disease Treatment
Thionamides (mainly methimazole)
 • Chance of remission in up to 2 years
 • No
Graves' Disease ... Treatment Thionamides ... mendesthiagob #Graves #Disease ... #Treatment #Management ... #endocrinology
Carpal Tunnel Syndrome 
Compression of median nerve 
Risk Factors 
 • Obesity 
 • Female gender
Carpal Tunnel Syndrome ... rheumatoid arthritis, hypothyroidism ... connective tissue diseases ... Aromatase inhibitor Treatment
Hashitoxicosis

‘Leakage’ symptoms of active Hashimoto’s disease

- Hashitoxicosis (Htx) can occur during the initial hyperthyroid stage in
active Hashimoto’s disease ... of Hashimoto’s disease ... active Hashimoto’s disease ... Hashitoxicosis #Hashimotos #Endocrinology ... #Diagnosis #Pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... rare, gestational diseases ... Secondary hyperthyroidism ... #endocrinology ... #pathophysiology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
• Cushing's Disease ... • GH Deficiency ... Dwarfism) • Hypothyroidism ... Panhypopituitarism Treatment ... Diagnosis #Algorithm #endocrinology
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease

Autoimmune thyroid disease overlap syndrome
Hypothyroidism ... → Hypothyroidism ... develop spontaneous hypothyroidism ... Hashitoxicosis #Endocrinology ... #Pathophysiology