16 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... fraction • HTN #GrowthHormone ... #diagnosis #signs ... endocrinology #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... lipid • GH excess ... expansion (e.g. carpal ... metabolic abn #GrowthHormone ... endocrinology #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Accumulated micro-damage exceeds ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Triquetral Fracture
The triquetrum is the second most commonly fractured carpal bone. Look for the "pooping duck
"pooping duck sign ... "pooping duck sign ... Discharge with orthopedic ... Diagnosis #Management #Orthopedics ... #Sports #MSK
Scapholunate Dissociation
The spacing between all carpal bones should be 1-2 mm, look for the "Terry Thomas"
"Terry Thomas" sign ... ("Terry Thomas sign ... follow-up with orthopedics ... Diagnosis #Management #Orthopedics ... #Sports #MSK
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
joint => Force exceeds ... Dislocation #Diagnosis #signs ... #symptoms #msk ... #orthopedics #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Major trauma -> An excess ... Femur #Fractures #msk ... #orthopedics #diagnosis ... differential #causes #pathophysiology
Total Anomalous Pulmonary Venous Return (TAPVR)
 • Introduction
 • Classification
 • Pathophysiology of TAPVR
 • Presentation
Classification • Pathophysiology ... Classic “snowman sign ... Outcomes by Cara ... cardiology #peds #pediatrics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... TendonRupture #diagnosis #signs ... #symptoms #pathophysiology ... #msk #orthopedics