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diagnosis differential hematology treatment lupus sle classification erythematosus neurology oncology vasculitis video abdominal ana anterior antibodies antinuclear arteritis behcet cardiology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... complications (AQP4-positive ... autoimmune disorders (Systemic ... #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Skin lesions • Positive ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination This 57 yo WM reported to clinic complaining of
Scleritis - Slit Lamp Ocular ... WM reported to clinic ... and had no other symptoms ... which came back positive ... for further systemic
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 Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... likely it will be clinically ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... reconstituted immune system ... skin lesions, ocular ... Zoster flare, ocular ... Differential #Diagnosis #Management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... months to years) Systemic ... comparison #table #rheumatology
Rare Causes of Abdominal Pain • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
- May involve symptoms ... cardiovascular system ... neuropsychiatric symptoms ... Carnett's sign ... incisional hernias: clinical
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... signs/sx of inflammation ... Biopsies remain positive ... them, but urgent rheumatology ... #Management
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... from a seated position ... (GBS), systemic ... (LEMS), systemic ... myopathy #diagnosis #management
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