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management diagnosis treatment ulcerative gastroenterology 1 5asa bowel cdi checkpointinhibitor clostridioides clostridium differential fatigue immune infection infectiousdiseases inflammatroy mild mimickers
Persistent UC Symptoms Despite 5-ASA Therapies • Assess for Drug Adherence • Disease Activity Assessment (bloody
Persistent UC Symptoms ... Drug Adherence • Disease ... Rule-Out Infection, Cdiff ... JAK Inhibitor Algorithm ... Treatment #Management #Algorithm
Relapsing Acute Severe Ulcerative Colitis - Management Algorithm Loss of Response: • (Re)consult Colorectal Surgery • Assess
Severe Ulcerative Colitis ... Adherence • Assess Disease ... Diff. & CMV COVID ... #UC #Management ... #Algorithm #IBD
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
Difficile Infection ... → Fulminant Colitis ... Perforation) Pathophysiology ... immunocompromised, IBD ... ciab549 #CDI #Cdiff
IBD Mimics Infectious - Always RULE OUT infection (CMV, C. diff esp.) obtain travel & exposures history:
infection (CMV, C. diff ... Salmonella • Colon: C. difficile ... intestine: Behcet's disease ... lymphomas, others) #IBD ... inflammatroy #bowel #disease
Mild-to-Moderate Ulcerative Colitis - Management Algorithm Curcumin: • Natural phytochemical from turmeric • 2g/day divided in 2-3
Budesonide and UC ... dosing if liver disease ... formulations • Difficult ... #UC #Management ... #treatment #IBD
Fatigue and IBD Algorithm • 40-50% patients have fatigue despite clinical remission • Risk factors: BMI,
Algorithm • 40- ... Prevalence Crohn's > UC ... Pearls: • IDA and ... differentiate IDA ... fatigue despite disease
Immune Checkpoint Inhibitor-Mediated Colitis Grade of Disease Severity: • G1: Increase < 4 BMs/day over baseline; mild
Inhibitor-Mediated Colitis ... Grade of Disease ... Diff, Stool cx, ... diagnosis #management #algorithm ... #IBD
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