76 results
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... cinacalcet to the first-line ... treatments inhibits ... #Pharmacology #Pathophysiology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
- Potentially Life ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #SideEffects #Psychiatry
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
complications) 2) Lines ... and Tubes • Central ... felt to be due to central ... venous line, it ... #candidiasis #treatment
Addictions: Pathogenesis

Mesolimbic Dopaminergic Pathway:
 • Dopaminergic neurons in Ventral Tegmental Area (VTA) in midbrain under continuous
Dopaminergic neurons in Ventral ... administration and poor control ... Pattern: Impaired Control ... Drug #Addiction #Pathophysiology ... #Psychiatry #Mesolimbic
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
- Distorted central ... Distortion of lines ... grid of straight lines ... blind spots in central ... MacularDegeneration #pathophysiology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Mania or Mania-Like ... Decreased Inhibitory control ... activity -> Decrased central ... Differential #Diagnosis #Pathophysiology ... #Psychiatry
Anaphylaxis: Treatments (Acute)
Additional Info:
 • IV steroids may be considered for prevention of late phase reactions.
Anaphylaxis: Treatments ... Treatment: • ... Epinephrine (1st line ... treatment) 1:1000 ... #Management #pathophysiology
SSRI Initiation
How long before increasing dose?
 • 4 wks. Initial response in 2-4 wks, max response
Longest half life ... Shortest half life ... Initiation #depression #psychiatry ... #treatment #management
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
-> Potentially life ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Hyperacute Hypoxemia - Workup and Management
Differential Diagnosis: Aspiration, Flash Pulmonary Edema, Mucous Plugging, Bronchospasm, Pulmonary Embolism,
Targeted Exam: Mental ... Exam, POCUS (B-lines ... Edema: Lasix + BP control ... diagnosis #Management #treatment