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oncology rheumatology dermatomyositis differential disease management agglutinin anemia antimda5 antimda5dm antinxp2 antinxp2dm behcet cell chronic cll cold dermpath gammopathy hemolytic
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... - Differential Diagnosis ... nemaline myopathy Cutaneous-centered ... #Gammopathy #Clinical ... #hematology #oncology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
the context of cutaneous ... Vasculitis #dermpath #dermatology ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... presentation) • Cutaneous ... Monoclonal IgM ... hemolytic #anemia #hematology ... #diagnosis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... chest (in a V-sign ... Inverse Gottron’s sign ... auricular papules Clinical ... #dermatology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... vasculitis) • Cutaneous ... Behcet syndrome (Clinical ... refractory disease : monoclonal ... #management #signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
) - Clinical symptoms ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology ... #Workup
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... chest (in a V-sign ... shoulders (in a shawl sign ... auricular papules Clinical ... #dermatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... Diagnosis? ... tissue composed of monoclonal ... EMD myeloma Diagnostic ... #Workup #Hematology
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