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hematology management cll differential leukemia lymphocytic microscopy oncology agglutinin aiha algorithm atlas autoimmune bacilliformis bartonella bloodcell cold common cvid disease
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... or negative - Smear ... C3 positive - Smear ... agglutination, rouleaux ... #diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... arrow) Peripheral smear ... #anemia #Hematology ... #Pathology #Smear
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Multiple myeloma Rouleaux ... : Chronic liver ... #differential #diagnosis ... #hematology #microscopy
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Peripheral Smear ... blood loss, Acute hemolysis ... , deficiency anemia ... • Infections: Chronic
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... anemia • Cold ... IgM) • Blood smear ... #anemia #hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Lutzomyia verrucarum Clinical ... lysis → severe hemolytic ... anemia, jaundice ... Nodular → Mular DIAGNOSIS ... phase: Peripheral smear
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... • Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... #hemeonc #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... and autoimmune hemolytic ... anemia) • Systemic ... Malignancies • Chronic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Peripheral smear ... • Neutropenia, anemia
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