13 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... bilirubin LDH Peripheral ... smear Haptoglobin ... #Anemia #Laboratory ... workup #diagnosis #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Anemias (AIHAs) ... Diagnosis #Algorithm #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Blood #Smear # ... Analysis #hematology ... interpretation #clinical
Peripheral blood eosinophils, Phase contrast microscopy, time lapse, 100x |Olympus CH30|

Carlos Martínez Figueroa @CarlosMartnezF7

#eosinophils #Peripheral #blood
Peripheral blood ... #eosinophils #Peripheral ... #blood #smear # ... clinical #microscopy ... #hematology #timelapse
Peripheral blood neutrophil, phase contrast microscopy, time lapse, 100x. Olympus CH30

Carlos Martínez Figueroa @CarlosMartnezF7

#neutrophil #Peripheral #blood
Peripheral blood ... #neutrophil #Peripheral ... #blood #smear # ... clinical #microscopy ... #hematology #timelapse
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... smear changes are ... #anemia #Hematology ... #Pathology #Smear
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Smear concerning ... → Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... Diagnosis #Algorithm #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... Dehydrogenase ↑ - Peripheral ... Blood Smear ↑ abnormal ... Differential #Diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... the range of Peripheral ... blood smear - Shows ... anemia Indirect ... Diagnosis #Workup #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... anemia • Cold ... IgM) • Blood smear ... #anemia #hematology