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diagnosis management lupus disease erythematosus syndrome classification rheumatoid signs symptoms vasculitis activation adultonset ana angiography antibodies antinuclear arteritis behcet comparison
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (SLE) General: ... 50%): Pleurisy / effusion ... of hip (rare), Arthritis ... symptoms #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Juvenile Idiopathic Arthritis ... scleroderma), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis ... ANA #patterns #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus Clinical ... cutaneous lupus • Arthritis ... or pericardial effusion ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... solid cancers • Systemic ... Pulmonary: pleural effusion ... management #treatment #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... fever syndromes Clinical ... Fever is the main clinical ... erythematosus [SLE ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... Lungs: • Pleural effusions
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... association • M > F Clinical ... Oral aphthae : SLE ... : SLE, Reactive ... signs #symptoms #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... nodules, joint effusions ... narrowing) • Ultrasound ... Diagnosis: CLINICAL ... diagnosis #management #rheumatology
Retinal Vasculitis in Takayasu’s Arteritis- ...Ophthalmologic examination revealed severe impairment, with perception of only light in
in Takayasu’s Arteritis ... Takayasu’s arteritis ... is a rare, systemic ... leads to decreased perfusion ... #NEJM #clinical
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