13 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Systemic Lupus (SLE ... 50%): Pleurisy / effusion ... of hip (rare), Arthritis ... symptoms #diagnosis #rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
nodules, joint effusions ... narrowing) • Ultrasound ... Diagnosis: CLINICAL ... exam and imaging Treatment ... diagnosis #management #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Fever, Arthralgia/arthritis ... Pulmonary: pleural effusion ... diagnosis #management #treatment ... #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Oral aphthae : SLE ... : SLE, Reactive ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... comparison #table #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus Clinical ... cutaneous lupus • Arthritis ... or pericardial effusion ... Classification #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... Lungs: • Pleural effusions ... Erythematosus #Diagnosis #Rheumatology
Retinal Vasculitis in Takayasu’s Arteritis- ...Ophthalmologic examination revealed severe impairment, with perception of only light in
in Takayasu’s Arteritis ... Takayasu’s arteritis ... leads to decreased perfusion ... and initiated treatment ... #NEJM #clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... erythematosus [SLE ... Treatment: • Corticosteroids ... #Rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis: • Clinical ... Confirmatory test ↑Se ... Can consider re-challenge ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc