17 results
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
- Cognitive Changes ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
- Cognitive Changes ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... anticoagulant (e.g ... conformational changes ... conformational change ... #Pharmacology #Pathophysiology
Pediatric SVT - Management Algorithm
Identify SVT:
 • HR not variable
 • Abrupt rate changes
 • Infants:
• Abrupt rate changes ... : HR > 180bpm ECG ... Monitors, Pads AP Stable ... Signs of shock or
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Heparin) • Sodium-channel ... • Increased EC ... differential #diagnosis #pathophysiology ... #pharmacology #
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
is not desired (e.g ... is not desired (e.g ... Inotropes #comparison #table ... #pharmacology # ... criticalcare
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... tinnitus, visual changes ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
whose positive charges ... whose positive charges ... lose a positive charge ... #foamed #criticalcare ... diagnosis #treatment #pharmacology
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
100 Dosing: 250 mcg ... tablet once daily ... increase to 500 mcg ... have been a few changes ... #Indications #Pharmacology
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
differential - Beta-HCG ... oral secretions (e.g ... monitoring (vital signs ... Beta-blockers, calcium channel ... Checklist #Management #CriticalCare