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diagnosis hematology algorithm causes eosinophilia leukemia basophilia basophils cll comparison cough diffuse diseases eosinophilic lad lung lymphadenopathy lymphocytic mds myelodysplasia
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Pseudotumor - Infectious ... • Acne • Allergy ... Fatigue • Acute ... Age > 50 • Chronic ... #Oncology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... released during an allergic ... reaction or asthma ... Disorders: • Chronic ... ’s Disease • Asthma
Cough - Diagnostic Schema Infectious: URTI, LRTI, Bacterial, Viral Irritant/Exposure: Allergic, Post-infectious, Pneumonitis, ACEi, PTX, Foreign Body Airway Disease:
Irritant/Exposure: Allergic ... , Post-infectious ... Airway Disease: Asthma ... Diagnosis #Schema #Acute ... #Chronic #Differential
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... Rhinitis - Allergic ... Dermatitis - Asthma ... Mastocytosis - Acute ... Hypereosinophilic Syndrome - Chronic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... → Refer to hematology ... : Chronic infections ... post-splenectomy, Exercise, Allergic ... Thrombocytosis #Platelets #Differential
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases • Acute ... cough, SOB • Chronic ... loss, malaise • Allergic ... , CNS, skin • Infectious ... Diseases #pulmonary #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... or functional neutropenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... Cytopenias: • Neutropenia ... ’s lymphoma or acute ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myeloproliferative Disease • Neutropenia ... • Parvovirus infection ... blood count with differential ... #oncology
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