11 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Malaise, bleeding, infections ... pain, bleeding, infections ... or functional neutropenia ... #Hematology #Oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... released during an allergic ... reaction or asthma ... Disorders: • Chronic ... ’s Disease • Asthma
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Pseudotumor - Infectious ... • Acne • Allergy ... History of Bleeding, Infection ... Age > 50 • Chronic ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... Cytopenias: • Neutropenia ... #Chronic #Lymphocytic ... workup #oncology #hematology
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... Rhinitis - Allergic ... Dermatitis - Asthma ... Primary: - CML ... Hypereosinophilic Syndrome - Chronic
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... • Eosinophilic Leukemia ... : Asthma, Eczema ... eosinophilia) • Infectious ... insufficiency, Chronic
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Thrombocytosis): • Acute infection ... hemorrhage) • Chronic ... myeloid leukemia ... (CML) - Dr.
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... Complications: 1) Infection ... PRCA, autoimmune neutropenia ... #hematology #hemeonc
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Immunocompromised Host - Differential ... Encapsulated Bacteria Cell ... Neutropenia or ... Bronchitis • Chronic ... Algorithm #Causes #Hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
2nd pass = Chronic ... • Parasitic infections ... Causes: • Mast cell ... #Diagnosis #hematology ... #allergy