47 results
diagnosis algorithm oncology anemia classification rheumatology workup hemolytic leukemia management thrombocytosis disorders eosinophilia hemolysis hepatitis injury intravascular liver lymphocytic thrombocytopenia
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... malignancies • Infection ... Myelofibrosis Stem cell ... #Differential # ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... ) (e.g. lupus, CLL ... spherocytosis) • Infections ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Hemolysis - Differential ... • Sickle cell ... circulation - Infections ... #Hematology
Causes of Leukocytosis and Leukopenia - Differential Diagnosis • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... and Leukopenia - Differential ... Neoplastic • Neutropenia ... #Diagnosis #causes ... #hematology
Isolated Neutropenia - Differential Diagnosis Algorithm Chronic (>3 months): • Extrinsic: Vitamins • Intrinsic: Congenital, Inflammatory Transient: •
Isolated Neutropenia ... - Differential ... Diagnosis Algorithm Chronic ... , Non-infectious ... Diagnosis #Algorithm #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Disorders: • Chronic ... ’s Disease • Asthma ... #Diagnosis #causes ... #hematology #basophils
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Neutropenia - Differential ... Antineoplastic Viral Infection ... Idiopathic - Chronic ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... -> AML: Blast crises ... pain, bleeding, infections ... or functional neutropenia ... #Leukemia #Hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... deficiency) • Infection ... Myelofibrosis • Chronic ... #Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Myelofibrosis Infectious ... : • Acute or Chronic ... #Hematology
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