10 results
Differential for the Child with Petechiae or Purpura
 - Non-thrombocytopenic
 - Thrombocytopenia

#Diagnosis #Peds #Pediatrics #Petechiae #Purpura
Differential for ... with Petechiae or Purpura ... #Diagnosis #Peds ... #Pediatrics #Petechiae ... #Purpura #Differential
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... algorithmic approach can help ... presents in thrombocytopenic ... palpable, the differential ... #Diagnosis #Dermatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... Microangiopathy #thrombocytopenic ... #purpura #TTP # ... #Comparison #Diagnosis ... #Table #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential ... Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... #Differential # ... Diagnosis #hematology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... - Fanconi anaemia ... Bruising #Causes #peds ... #pediatrics #diagnosis ... #differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... #workup #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
features: Hemolysis, Thrombocytopenia ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp # ... HELLP #AFLP
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... result in severe anemia ... WBC count and differential ... #Workup #Hematology