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causes hemolysis algorithm bruising dermatology extravascular hemolyticuremicsyndrome intravascular nonpalpable palpable rheumatology schistocytes table testing thrombocytopenic thrombotic ttp workup
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
hemolytic anemia ... coagulation (DIC) - HELLP ... purpura (TTP), ... syndrome (HUS) ... #diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
- TTP VS HUS ... Often hard to differentiate ... #purpura #TTP # ... #Comparison #Diagnosis ... #Table #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... syndrome (ST-HUS ... Drug-induced thrombotic microangiopathy ... anemia" • HELLP ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - DIC, TTP, HELLP ... , HUS, aHUS, mechanical ... #Anemia #Differential ... #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic ... anemia - Splenomegaly ... Diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Non-immune - Haemolytic ... - Fanconi anaemia ... Bruising #Causes #peds ... #pediatrics #diagnosis ... #differential #
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