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rheumatology management autoantibodies causes dermatology algorithm ana antinuclear associations clinical erythematosus hepatology lupus pathology systemic vasculitis anemia comparison disease fingernail
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific Antibodies ... Anti-Synthetase Syndrome ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Diagnosis Algorithm ... Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG) SAAG ≥ 1.1: • Cirrhosis • Portal
Ascites Differential ... Diagnosis Table ... • Nephrotic syndrome ... #Diagnosis #Table ... Gradient #SAAG #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... B12 - Anti-IF Antibodies ... Myelodysplastic Syndromes ... #Causes #Hematology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
others (RNP, aPL antibodies ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... #diagnosis #associations ... #table
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Sensitive Antibodies ... Donath-Landsteiner Antibodies ... Cold Agglutinin Syndrome ... younger pts) Differential ... hemolytic #anemia #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
SLE), Sjogren's Syndrome ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Nail Findings & Associated Conditions Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... fingernail #pathology #differential ... #diagnosis #dermatology ... #nails #table #
Nail Findings & Associated Conditions Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... fingernail #pathology #differential ... #diagnosis #dermatology ... #nails #table #
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