53 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
yrs old; F>M Signs ... /Symptoms: - Fever ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Disease, Rheumatoid Vasculitis ... Rheumatoid Nodules, Pulmonary ... Arthritis #RA #diagnosis ... #rheumatology #signs ... #symptoms
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
hard nodules in fingers ... CREST #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
polyarthritis • Pulmonary ... exertion • Neurologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs ... #Pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... progressing GN • New pulmonary ... episcleritis as well as inner ... Presentation - Systemic Symptoms ... purpura: strong sign
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... pain Psychiatric Symptoms ... Alteration in hunger ... Hyperparathyroidism #diagnosis ... Secondary #Tertiary #pathophysiology
Diffuse Systemic Sclerosis (Scleroderma)
 - Pulmonary Fibrosis -> Crackles, Abnormal CXR
 - Pulmonary Hypertension, Right Heart
Scleroderma) - Pulmonary ... Abnormal CXR - Pulmonary ... #Scleroderma #pathophysiology ... #signs #symptoms ... #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Presentation: Systemic Symptoms ... purpura: Strong sign ... affects the skin, neurologic ... • Progressive symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... pulmonary TB PE ... decreased reflexes Pathophysiology ... for concomitant pulmonary