9 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... the Nephron #DrugInduced ... AKI #Nephrology #Pathophysiology ... #Pharmacology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Glomerular Disease: Drug ... , NSAIDs, Chemotherapy ... tubular injury: Antibiotics ... @kdjhaveri #DrugInduced
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications ... #druginduced
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... Kat_Watson #DrugInduced ... #Differential #Pharmacology ... #Pathophysiology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
controlled DM • Chemotherapy ... reactions Common Drugs ... • Recent IV potassium ... Beta blockers • Antibiotics ... diagnosis #causes #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
controlled DM • Chemotherapy ... reactions Common Drugs ... • Recent IV potassium ... Beta blockers • Antibiotics ... diagnosis #causes #potassium
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease

Active Helicobacter pylori—associated ulcer
1. Treat with anti—H pylori
bismuth subcitrate potassium ... completion of antibiotic ... the preferred drugs ... Treatment #Management #Pharmacology
Allopurinol Pharmacology Summary

Xanthine oxidase inhibitor blocking the formation of new uric acid
Initiate 1-2 days prior to
Allopurinol Pharmacology ... days prior to chemotherapy ... hypersensitivity Drug ... #Allopurinol #Pharmacology ... #pathophysiology