8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... : >3 symptoms, or ... initiation • Differential ... #hematology #oncology
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
↑ "Right Sided-Symptoms ... , ↑↑peripheral edema ... Hyper-eosinophilc Syndrome ... #Causes #differential ... #cardiology #algorithm
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
disease, Cancer chemotherapy ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... the underlying cause
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Definition: • Severe adverse ... • Facial Edema ... in 70% of cases ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... capillary leak syndrome ... , nausea, pain) ... #oncology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Diagnosis Framework ... Non-compressive Spinal Cord Causes ... Metabolic: - Chemotherapy ... MCTD, Sjogren syndrome ... #algorithm
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... blood count with differential ... ) • Intensive chemotherapy ... #diagnosis #hematology ... #oncology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
acute coronary syndrome ... the determined cause ... #diagnosis #differential ... #algorithm #management ... icu #clinical #pharmacology