51 results
Hemolytic anemia in Wilson's disease

#Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
anemia in Wilson's disease ... #Wilsons #Disease ... hemolytic #anemia #Hematology ... #pathophysiology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Disease Clinical ... cancers • Systemic diseases ... autoinflammatory diseases ... management #treatment #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
the population Disease ... onset - Mostly ... Autoimmune diseases ... , liquids The onset ... Urticaria #diagnosis #rheumatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
: Diffuse skin disease ... : Limited skin disease ... , Young age of onset ... Autoantibodies #diagnosis #rheumatology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Colitis and Crohn’s Disease ... Influenza • Chickenpox ... Diagnosis #causes #hematology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... factor for Late Onset ... factors for Early Onset ... AlzheimersDisease #Dementia #pathophysiology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... - Pathophysiology ... of disease and ... #Pathophysiology ... Complications #Hematology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... terms of time of onset ... Cardiovascular disease ... endocrinology #pathophysiology
Vaccines - Impact Timeline
Diphtheria
Polio
Pertussis
Hepatitis B
Measles
Chickenpox
Hepatitis A
Mumps
Rubella

Bubbles represent reported U.S. cases, but not all diseases were notifiable
Vaccines - Impact Timeline ... Hepatitis B Measles Chickenpox ... cases, but not all diseases ... Vaccines #Impact #Timeline
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... SLE+++, Adult-onset ... Still disease, ... treatment #summary #rheumatology