10 results
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
, cholestatic, immune-mediated ... extra-hepatic bile ducts, commonly ... • COLITIS - PSC-IBD ... judicious use of ERCP ... with UDCA remains common
IBD Mimics
Infectious - Always RULE OUT infection (CMV, C. diff esp.) obtain travel & exposures history:
IBD Mimics Infectious ... syndrome, CVID (common ... immunodeficiency) • Ulcers in ... associated with ... (NSAIDS, immuno-therapy
Dilated Distal Common Bile Duct on POCUS

Male with RUQ abdominal pain for 2 days.  GB
Dilated Distal Common ... show elevated WBC ... ERCP/cholecystectomy ... pancreatitis or cholangitis ... RJonesSonoEM #Dilated #Common
Proposed Schema for the Management of Pruritus in Primary Biliary Cholangitis (PBC). 

Cholestyramine up to 4g
Management of Pruritus in ... (PBC). ... Recirculating System; CBD ... , common bile duct ... #Hepatology #Algorithm
Immune Checkpoint Inhibitor-Mediated Colitis
Grade of Disease Severity:
 • G1: Increase < 4 BMs/day over baseline; mild
Immune Checkpoint ... Inhibitor-Mediated Colitis ... Consult GI • Labs: CBC ... consider early in ... diagnosis #management #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Necrotizing, pauci-immune ... respiratory tracts Immune ... (Commonly MPO-ANCA ... : (± 100 % Commonly ... Lab Tests: • CBC
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune ... Epidemiology: • Most common ... in the west • ... Lymphocytosis on CBC ... Contamination, colitis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... context of primary immune ... titers > 1:80 • CBC ... Kidney disease common ... Malignancy Associated
CASTLEMAN DISEASE
Disorder of the immune system with excessive production of IL-6

Castleman’s disease is a rare, heterogeneous
Disorder of the immune ... • Associated ... CBC: Anemia and ... HHV-8-associated ... crucial, as HHV-8 is associated
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Diagnosis: On the CBC ... thrombocytosis, only other commonly ... ET-associated mutation ... hemoproliferative disorder associated ... • Treatment algorithms