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diagnosis management differential hemophagocytic hlh lifecycle lymphohistiocytosis parasite american antimda5 antimda5dm bileduct celiac clonorchis dermatitis dermatology dermatomyositis dilatation dilated fat
Causes of Biliary Dilatation - Differential Diagnosis • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy •
Causes of Biliary ... Physiological: ↑ Age, Cholecystectomy ... cyst, Caroli's disease ... #Dilatation #causes ... diagnosis #hepatology #gastroenterology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
severity of the disease ... Decreased CD4 ... + and CD8+ T cell ... counts and a raised CD4 ... +/CD8+ ratio are
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
Causes of Fat Malabsorption ... Differential Diagnosis Biliary ... , celiac disease ... • IBD- CD, UC ... Differential #Diagnosis #Causes
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... • Autoimmune diseases ... Adult-onset Still disease ... treatment #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... hepatitis, primary biliary ... • Nephrogenic DI ... Sjogrens #Syndrome #Rheumatology
Trypanosomiasis - Trypanosoma cruzi Life Cycle 1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
a blood meal (passes ... Amastigotes multiply by binary ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Clonorchis sinensis (Chinese or oriental liver fluke) Life Cycle The trematode Clonorchis sinensis (Chinese or oriental liver
foodborne pathogen and cause ... of liver disease ... discharged in the biliary ... and ascend the biliary ... LifeCycle #Parasite #CDC
Celiac disease is an immune-mediated, multisystem disorder that affects genetically susceptible individuals who are exposed to
Celiac disease is ... CD can be associated ... and idiopathic diseases ... (primary biliary ... performed in select cases
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... ▪ Autoimmune diseases ... Pathophysiology ... of NK cells and CD8 ... Diagnosis #Management #Hematology
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