2817 results
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Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
• Hereditary Cholestatic ... , and some cases ... ) Intrahepatic cholestasis ... miscellaneous causes ... #differential #causes
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Enzymes (LFTs) - Causes ... Hepatocellular and Cholestatic ... Hepatocellular or Cholestatic ... R ≤ 2 = Cholestatic ... Hepatocellular #Cholestatic
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Thrombus, Vasospasm Cholestatic ... Hepatitis, TB Cholestatic ... Differential #Diagnosis #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... poisoning, ETOH Cholestatic ... elevation Labs in Cholestatic ... epithelia: - Cholestasis ... ALT: typical of cholestatic
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Hepatocellular • Cholestatic ... Diagnosis #Algorithm #Causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Tests/Enzymes: • Cholestatic ... Diagnosis #Algorithm #causes
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Others • Cholestatic ... Diagnosis #Algorithm #Causes
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
= intrahepatic cholestasis ... non-ICU vs ICU causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... of Intrahepatic cholestasis ... - Pruritis - Cholestasis
Dematoses in Pregnancy - Specific Skin Conditions Non-Pruritic • Pustular psoriasis of pregnancy • Impetigo Herpetiformis Pruritic -
• Intrahepatic cholestasis ... Diagnosis #Algorithm #causes
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