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causes algorithm leukemia workup chronic cll hemolytic lymphocytic management platelet purpura bleeding classification extravascular gap globulin hemeonc hemepath hemolysis hodgkins
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
of Bleeding / Bruising ... - Differential ... Diagnosis Algorithm ... Thrombocytopenia ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... • Rheumatic disorders ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... and Aggregometry ... Gplb receptor • Thrombcytopenia ... #hematology #hemepath ... diagnosis #Aggregometry
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... #Differential # ... #Workup #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Purpura or Easy Bruising ... Congenital - Rare disorders ... bypass Vascular disorders ... #Causes #peds #pediatrics ... #diagnosis #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... discoloration) • Liver cirrhosis ... Systemic #Secondary #dermatology ... #Differential # ... Diagnosis #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... 5) Symptoms of anemia ... or thrombocytopenia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
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