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diagnosis differential management rheumatology causes dermatology hyperpigmentation lupus skin cvid erythematosus hodgkins hypogammaglobulinemia hypopigmentation immunodeficiency immunology lymphoma lymphomas lymphoproliferative nephritis
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... : • Class I - ... mesangial LN • Class ... proliferative LN • Class ... Membranous LN • Class
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... Differential Diagnosis Algorithm ... versicolor (more commonly ... #skin #dermatology ... #causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... are present • Classic ... lymphadenopathy more diffuse ... #Classification ... pathophysiology #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Malignancy (e.g. hematologic ... pneumonitis • Diffuse ... enteropathy, and diffuse ... Kidney disease common
Skin Hyperpigmentation - Differential Diagnosis Algorithm Diffuse: • Tanning • Adverse cutaneous drug eruption • Addison's disease
Diffuse: • Tanning ... versicolor (more commonly ... Hyperpigmentation #disorders ... #skin #dermatology ... #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... Immunodeficiency disorder ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... ) Classification ... (NSHL) - (most common ... lymphoma #diagnosis #classification ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Drug Associated (Commonly ... Associated: (± 100 % Commonly ... • ANA (Suggest CTD ... vasculitis, and SLE ... #classification
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