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diagnosis differential cardiology management nephrology rheumatology nephritis antiarrhythmics comparison pathophysiology pharmacology preoperative risk treatment accaha allergy asa chf clinicopathology congestive
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Primer Class I - ... #Nephritis #SLE ... #Classification ... #Classes #differential
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... : • Class I - ... mesangial LN • Class ... proliferative LN • Class ... Membranous LN • Class
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... , Class Ill or IV ... #EULARACR #Classification ... #Criteria #SLE
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... treat non-renal SLE ... immunosuppression to treat class ... therapy to treat class
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
: CLASS 1 - Sodium ... duration: - CLASS ... duration - CLASS ... & AP duration CLASS ... #Classes #pathophysiology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... Discontinuation of causal ... Erythematosus (SLE ... Positive in 60-80% of cases ... #table #rheumatology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
: CLASS 1 - Sodium ... duration - CLASS ... duration - CLASS ... & AP duration CLASS ... #Classes #pathophysiology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... reabsorption • RTA ... (MPA) • SLE ... #Causes
Causes of Polyneuropathy - Differential Diagnosis Algorithm • Metabolic: DM, Hypothyroidism, CKD, Cirrhosis, Nutritional deficiency •
Causes of Polyneuropathy ... Differential Diagnosis Algorithm ... Paraneoplastic, CTD ... (SLE, RA, Sjogren ... #causes #neurology
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Causes of Hemoptysis ... Differential Diagnosis Algorithm ... Vasculitis • Lupus ... Differential #Diagnosis #Algorithm ... #Causes #Pulmonary
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