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diagnosis nephrology management differential rheumatology treatment sle comparison criteria diseases disorders erythematosus eularacr glomerular glomerulonephritis hematology lymphomas lymphoproliferative membranous microscopy
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Primer Class I - ... Proliferative Class ... IV - Diffuse Proliferative ... #Classification
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... : • Class I - ... mesangial LN • Class ... proliferative LN • Class ... Membranous LN • Class
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... immunosuppression to treat class ... therapy to treat class ... #Nephritis #Algorithm
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... II or V lupus nephritis ... , Class Ill or IV ... lupus nephritis
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V) Induction Therapy
Treatment Algorithm ... Nephritis (Class ... III/IV or Mixed Class ... #Treatment #Algorithm ... #Nephritis #management
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... • Lupus ISN/RPS ... class IV (diffuse ... Haemolytic-uraemic syndrome Nephrotic
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... differential #diagnosis #algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... lymphadenopathy more diffuse ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
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