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diagnosis management nephritis nephrology rheumatology treatment classification differential complications criteria erythematosus eularacr glomerulonephritis manifestations membranous mucocutaneous progressive proliferative rapidly rpgn
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Primer Class I - ... Minimal Mesangial Class ... Proliferative Class ... #Nephritis #SLE
Algorithm for the Treatment of Membranous Lupus Nephritis Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... treat non-renal SLE ... immunosuppression to treat class ... therapy to treat class
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... Classification: • Class ... mesangial LN • Class ... proliferative LN • Class ... Membranous LN • Class
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... > 0.5 g/24 hr, Class ... , Class Ill or IV ... lupus nephritis ... Classification #Criteria #SLE
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V) Induction Therapy
Treatment Algorithm ... Proliferative Lupus ... Nephritis (Class ... III/IV or Mixed Class ... #Treatment #Algorithm
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... hair follicles -> causes ... #SLE #Mucocutaneous ... Manifestations #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Post-strep GN, Lupus ... differential #diagnosis #algorithm
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