17 results
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... duration: - CLASS ... duration - CLASS ... Classification #Classes ... #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Classification: CLASS ... duration - CLASS ... duration - CLASS ... Classification #Classes ... #pathophysiology
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
inhibitors Other causes ... Ketoconazole Low ... NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm ... #differential #causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Causes of Iron Deficiency - Differential Diagnosis Algorithm
 • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Pregnancy, Lactation, Low ... achlorhydria: PPI or H2-blocker ... Differential #Diagnosis #Causes ... #Fe #algorithm
Table 2: Relative potency of topical corticosteroids*
TC are divided into four groups according to their potency
them into seven classes ... , [23] with class ... ultra potent and class ... drugs in each class ... general rule, low
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... Aldosterone • ENaC blockers ... Differential #Diagnosis #Algorithm ... #Causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Prolonged PT/PTT • Low ... • Elevated D-Dimer ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... staining): • Low ... differential #diagnosis #algorithm
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Most cases diagnosed ... collection with EDTA Pathophysiology ... pyrophosphate) blocks ... Phosphatase: • Other causes