18 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Primer Class I - ... Minimal Mesangial Class ... Proliferative Class ... Nephritis #SLE #Classification
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
: • Class I - ... mesangial LN • Class ... proliferative LN • Class ... chronic lesions • Class ... Membranous LN • Class
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic Lupus ... > 0.5 g/24 hr, Class ... , Class Ill or IV ... #EULARACR #Classification
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
: CLASS 1 - Sodium ... duration - CLASS ... duration - CLASS ... & AP duration CLASS ... #Classes #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... cellular antigen, leading ... , and systemic lupus ... Hypersensitivity #Types #Classification ... #Pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
: CLASS 1 - Sodium ... duration: - CLASS ... duration - CLASS ... & AP duration CLASS ... #Classes #pathophysiology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Systemic Lupus ... • Acne • Allergy ... Differential #Diagnosis #Algorithm
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Treatment Algorithm ... Proliferative Lupus ... Nephritis (Class ... III/IV or Mixed Class ... #Treatment #Algorithm
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... cell surfaces causes ... immune reaction, leading ... causes development ... #Types #Classification
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... immunosuppression to treat class ... therapy to treat class ... #Membranous #Lupus