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diagnosis management differential hematology neurology rheumatology shock treatment criticalcare hemophagocytic hlh lymphohistiocytosis overview antiarrhythmics beriberi cardiology cellulitis cerebritis chloride classes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Low Grade - Slow growing ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Thrombocytosis: cells ... tourniquet while drawing ... 7) - principal cells ... #causes #potassium ... #high #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... , Hb), Hepatic dysfunction ... Drugs, Unknown cause
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Pathogenesis and clinical ... accumulates in cells ... Glycosylation - AGE cause ... increasing cytogenetic dysfunction ... #DiabeticFoot #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Differential Diagnosis Algorithm ... smooth muscle cells ... gastrointestinal osmotic gradient ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... Schistocytes, helmet cells ... Treat primary cause ... Coagulation #diagnosis #causes
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... disease Systolic dysfunction ... Diastolic dysfunction ... pulmonary Langerhans cell ... #Differential #Causes
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... and increased B-cell ... renal failure Clinical ... symptoms are not caused
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... progressive organ dysfunction ... specific) COMMON CLINICAL ... complement • Classification
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... death Common Clinical ... #differential #causes ... #classification
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