9 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Low Grade - Slow growing ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... death Common Clinical ... #Classification ... differential #causes #classification
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
rapidly progresses: cell ... death -> end-organ dysfunction ... death Common Clinical ... #Classification ... differential #causes #classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... risk death), T-cell ... CLINICAL RECOGNITION ... CLINICAL FEATURES
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... 64%) • Renal dysfunction ... (16%) • Shock ... Schistocytes, helmet cells
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... progressive organ dysfunction ... specific) COMMON CLINICAL ... complement • Classification
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Pathogenesis and clinical ... accumulates in cells ... essential for cell ... increasing cytogenetic dysfunction ... #DiabeticFoot #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Infection/Sepsis/Shock ... marrow or stem cell ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... elevated white blood cell
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
various tissues, leading ... populations) CLINICAL ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... Birbeck granules (EM