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diagnosis management hematology syndrome apml cardiology causes childhood criticalcare differentiation disorders encephalopathy erythematosus immunecompromised immunization immunocompromised infectiousdiseases lupus lymphomas lymphoproliferative
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... pattern of spread, B symptoms ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #algorithm
Shock Types - Classification State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... #Classification ... #criticalcare #differential
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... Life-threatening organ dysfunction ... cellular/metabolic dysfunction ... • Pathophysiology ... • Symptoms: Fever
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
hemorrhagic rash; symptoms ... of shock • Mumps ... vessel collapse leading ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Diagnosis Algorithm ... Bacteremia/Septic Shock ... or Neutrophil Dysfunction ... Infection #Fever
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... Subacute-Acute: • Common: fever ... Diagnosis: >3 symptoms ... initiation • Differential ... severe APLS, organ dysfuxtion
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Infection/Sepsis/Shock ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... Neurological symptoms ... Reversible course Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Skin Disease Classification ... permanent alopecia Differential ... mild cognitive dysfunction ... Induced Lupus: • Symptoms
Palpitations - Differential Diagnosis Framework What? • It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... heart is pounding, racing ... or sinus node dysfunction ... Electrolyte imbalance • Fever ... AVNRT Red Flag Symptoms
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
Fever After International ... levels; dengue shock ... thrombocytopenia, and renal dysfunction ... and myalgias, symptoms ... #Travel #Differential
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