8 results
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
: Apixaban (25% ... renal clearance ... Anticoagulation #Hematology ... #Pharmacology # ... Apixaban #Rivaroxaban
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... Anticoagulation #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... rivaroxaban, and apixaban ... Rivaroxaban and apixaban ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
recent creatinine clearance ... (calculated using ... interruption per treatment ... inhibitor) • Apixaban ... #pharmacology #
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
anticoagulant treatment ... Antidotes: • Apixaban ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... for the treatment ... for appropriate dosing ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... treatment #medications ... decisionaid #cardiology #hematology ... #warfarin #dosing