12 results
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Renal Dosing ... Apixaban (25% renal clearance ... @Bloodman #DOAC ... Anticoagulation #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... anticoagulants (DOACs ... for appropriate dosing ... Anticoagulation #Management #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... metabolization of DOACs ... Chemotherapy #Oncology #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... recent creatinine clearance ... (calculated using ... interruption per treatment ... Perioperative #Management #Treatment
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
adsorption onto cancer ... subsequent enhanced clearance ... Diagnosis #Management #treatment ... #hematology #differential
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
B-LNH), solid cancers ... Unknown cause Treatment ... PTLD), allogeneic HSCT ... diagnosis #management #treatment ... #summary #rheumatology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
for 21% of all cancers ... • Allogeneic HSCT ... symptoms, unexplained hematologic ... abnormalities (↑ LDH), rising
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination

This 57 yo WM reported to clinic complaining of
phenylephrine was applied using ... patient was sent to rheumatology ... systemic workup and treatment ... Bennett & Bloom Eye Center ... #physicalexam #rheumatology
A quick infographic on the importance of sun protection and the various results of sun damage
causes #diagnosis #dermatology ... Skin Cancer. ... CA Cancer J Clin ... Mechanisms and treatments ... Dong K, Goyarts