14 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... association • M > F Clinical ... (Clinical Dx). ... #diagnosis #management ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Clinical Triad ... Central nervous system ... Triad #Diagnosis #Management ... #Rheumatology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
cephalosporin by Test ... carbapenems by Test ... rash eosinophilia systemic ... there is a strong clinical ... Prescription #algorithm #management
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... -15% If SLE is clinically ... suspected, tests ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... = systemic sx + ... the “Chewing gum test ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... female, asian • Systemic ... specific laboratory tests ... Disease #diagnosis #management ... workup #treatment #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
rendering the immune system ... adults in the west ... Orange or Hep C Clinical ... ’s CLL Scoring system ... • Richter’s Syndrome