27 results
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... intracellular, Aerobic - Cocci ... Inflammation: high fever ... Peripheral smear - Cocci
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
after bite • Fever ... is rare (< 10% cases ... ), cough (30% cases ... Infection #diagnosis #microbiology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... rapidly fatal • Causes ... BrighamChiefs #Fever ... #Hyperthermia #comparison
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
virus 7 HHV-7 Fever ... #Viruses #HHV #Microbiology ... #Diagnosis #Comparison
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
barns and lake houses ... • Prodrome: fever ... chills, myalgias, nausea ... management #treatment #microbiology
Doxycycline - Coverage and Indications
 • Staphylococci (S aureus + CoNS)
 • The tick stuff: Borrelia
• "Atypical" causes ... Bartonella, Q fever ... #pharmacology #microbiology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Fever/Chills/Joint ... (8%) - Gm - cocci ... Acute rheumatic fever ... Knee #Effusions #causes
Guide to Interpretation of Positive Blood Cultures

I arrange the potential Gram stain results that one can
rods, Gram(–) cocci ... Gram(+) cocci are ... Fewer positive cultures ... shaped GPR, these clues ... Interpretation #Laboratory #Microbiology
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Kawasaki Disease CDC Case ... years old with fever ... MISC #Kawasaki #Comparison
Microbial Etiology of Acute Pharyngitis - IDSA
Bacterial
 • Group A streptococcus - Pharyngotonsillitis, scarlet fever
 •
Pharyngotonsillitis, scarlet fever ... Pharyngoconjunctival fever ... #differential #causes ... #bacteria #microbiology