16 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... Nephrotic yndrome—podocyte ... diabetes)) #Glomerular ... #Classification
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC casts ... Syndrome #Comparison #Algorithm
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... Tubules (ATN) • Glomerular ... : Nephrotic, Nephritic ... #KidneyInjury #Causes ... Differential #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria, proteinuria ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... post-infectious GN Anti-Glomerular
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... present on repeat testing ... • Drugs Glomerular ... #Causes
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... range) proteinuria
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... infections are common causes ... of glomerular disease ... disorders #glomerular
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... Nephrocalcinosis causes ... #diagnosis #glomerular ... #proteinuria #nephrotic
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... infections are common causes ... of glomerular disease ... #glomerular #disease
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
SLE Hallmark = proteinuria ... therapy Goal: proteinuria ... by 12 months Classification ... Focal LN (<50% of glomeruli ... Diffuse LN (>50% of glomeruli