13 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
limb ischemia, bowel ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... vonWillebrand #Syndrome ... #treatment #hematology ... #differential
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Decompensated CHF ... Pneumothorax, Cardiac ... Abdominal compartment syndrome ... #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... , DIC, TMA • Cardiac ... Disease #diagnosis #management ... #treatment #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... sepsis), PE, DAH, CHF ... APML #diagnosis #management ... #hematology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
thrombosis, VTE) • Cardiac ... Behcet disease) Differential ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
acute coronary syndrome ... #diagnosis #differential ... #algorithm #management ... #table #foamed ... #heartfailure #chf
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... small and large bowel ... 5% of patients Cardiac ... Cytopenias • Cardiac ... Erythematosus #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... factors (examples: G-CSF ... #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Cerebrospinal fluid (CSF ... nose, tracheal collapse ... #Diagnosis #Rheumatology