30 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... Hypersensitivity #Types #Classification ... #Pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... #Immunology #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
cell antigens, leading ... to complement activation ... they activate complement ... reactions #types #allergy ... #table #classification
Lumbar stenosis guide we created to implement consistent radiology reporting across our multi-hospital network. 
Lumbar Central
we created to implement ... Canal Stenosis Grading ... Foraminal Stenosis Grading ... Spine #Report #Grading ... #Classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
degranulation, leading ... to an allergic ... antigen-surface complex, leading ... immune reaction, leading ... #Types #Classification
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis #differential
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
blood vessels, leading ... Activation of the complement ... Medication #Causes #Differential ... #Pharmacology #Pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Low Grade - Slow growing ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... Diagnosis #NonHodgkin #differential
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... tagged with C3 complement ... - Activate Complement ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
(HPS) HPS-differential ... Alveolar-arterial oxygen gradient ... HPS-severity classification