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UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020

Clinical Presentation
• Fever: hospitalized pts but
Evaluation Guide ... Presentation • Fever ... Biomarkers • WBC ... % if severe or ICU ... Guide #Diagnosis #Algorithm
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... tachycardia or fever ... likelihood of negative clinical ... hypotension or septic shock ... count on initial evaluation
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ICU ... /management of shock ... : • For most ICU ... pts a CBC and CMP ... bedside echo is never
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Evaluation of suspected ... old on day ≥7 of fever ... if they have no clinical ... purposes of this algorithm ... within 10 d of fever
Modified dengue severity classification, PAHO/WHO
Dengue without warning signs - DNWS:
 • Person who lives or has
dengue severity classification ... days and presents fever ... Shock evidenced ... bleeding: based on evaluation ... or ALT > 1000 IU
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
NETs), cytokines, complement ... CLINICAL RECOGNITION ... • Symptoms: Fever ... CLINICAL FEATURES ... , ventilation, ICU
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
just simply a clinical ... are excellent at evaluating ... essentially Cardiogenic Shock ... #differential #algorithm ... #criticalcare #icu
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... titers > 1:80 • CBC