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diagnosis rheumatology sle erythematosus table types allergy comparison hypersensitivity management reactions vasculitis criteria cryoglobulinemia cryoglobulins dengue differential disease druginduced eularacr
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Clinical Domains ... Constitutional domain: Fever ... anticoagulant • Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... 80% - Low complement ... management of SLE • Evolution ... #Systemic #Erythematosus
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... , seasonal hay fever ... Complement activation ... lupus erythematosus ... Hypersensitivity #Types #Classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 90% - Low complement ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... 80% - Low complement
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Anaphylaxis, Hay fever ... they activate complement ... glomerulonephritis, Systemic ... lupus erythematosus ... allergy #table #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... lupus erythematosus ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... • Low serum C4 complement ... lupus erythematosus ... diagnosis #types #classification
Modified dengue severity classification, PAHO/WHO Dengue without warning signs - DNWS: • Person who lives or has
dengue severity classification ... days and presents fever ... Shock evidenced ... bleeding: based on evaluation ... central nervous system
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Evaluation of suspected ... old on day ≥7 of fever ... if evidence of systemic ... if they have no clinical ... within 10 d of fever
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