146 results
diagnosis differential algorithm rheumatology nephrology management hematology pulmonary neurology pathophysiology dermatology cardiology clinical signs renal symptoms treatment acute aki classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive Glomerulonephritis ... pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... #Vasculitis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Necrotizing glomerulonephritis ... , pauci-immune glomerulonephritis ... • Glomerulonephritis ... tract, and often causes ... against MPO • Complement
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... Cryoglobulins Cause ... • Low serum C4 complement ... • Vasculitis
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... workup #diagnosis #glomerulonephritis
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
rapidly progressive glomerulonephritis ... ANCA Associated Vasculitis ... anti-GBM) 10%: - Low Complement ... - Normal Complement ... Renal Crisis, IgA Vasculitis
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... dysmorphic RBC, RBC casts ... staining (lg + complement ... MGPN • Complement ... Membranoproliferative #Glomerulonephritis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Membranoproliferative glomerulonephritis ... Post/pauci immune glomerulonephritis ... Hypocomplementemia #Low #Complement
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Hypocomplementemic Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... Hypocomplementemic #Urticarial #Vasculitis
Diagnosis and management of Polyarteritis Nodosa (PAN) Chapel Hill 2012 definition: Necrotizing vasculitis ofmedium or small arteries
Necrotizing vasculitis ... arteries without glomerulonephritis ... or vasculitis in ... involvement French Vasculitis ... Diagnosis #Management #Vasculitis
Spectrum of Glomerulonephritis Pathology - Common Diseases - Typical Presentation By Dr. John Roberts @John_K_Roberts #Glomerulonephritis #Spectrum
Spectrum of Glomerulonephritis ... John_K_Roberts #Glomerulonephritis ... Diagnosis #Nephrology #Causes
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