357 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 • SLE ... • Infection eg SBE ... ThePeanutKidney #Complement
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Erythematosus #SLE
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... 80% - Low complement ... management of SLE ... druginduced #lupus #sle
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement ... management of SLE ... Lupusreference #SLE
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Modified Sgarbossa Criteria - Diagnostic Checklist for diagnosing MI in LBBB or Pacemaker
1) Identify LBBB or
Should see "Appropriate ... main vector 3) Implement ... a) Concordant STE ... V1-V3 c) STE ... electrocardiogram #ecg #cardiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... tagged with C3 complement ... - Activate Complement ... classical pathway (see ... Complement Activation
Various wide complex tachycardia (WCT) differentiation algorithmic designs and algorithms.
The most commonly utilized approaches to differentiate
differentiation algorithmic ... designs and algorithms ... decision‐tree algorithms ... Electrocardiogram #Diagnosis #Cardiology ... #Algorithms
Cardiogenic Shock algorithm #algorithm #cardiology #cardiogenicshock #criticalcare #algorithm
Cardiogenic Shock algorithm ... #algorithm #cardiology ... #criticalcare #algorithm