59 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 90% - Low complement ... 40, F:M 9:1 • Clinical ... are evocative of SLE ... 80% - Low complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... 40, F:M 9:1 • Clinical ... are evocative of SLE ... 80% - Low complement ... management of SLE
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... Erythematosus (SLE ... Amy Chung, MD, MSc ... Joint #Disorders #msk ... Differential #Diagnosis #Algorithm
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... activation • Complement ... tagged with C3 complement ... classical pathway (see ... Complement Activation
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... Immunologic Criteria CLINICAL ... anticoagulant - Low complement ... #Rheumatology #SLE
Dysphagia - Differential Diagnosis Algorithm

Oropharyngeal Dysphagia 
Esophageal Dysphagia 
 • Upper 2/3 (striated muscle): stroke, NMJ
Differential Diagnosis Algorithm ... disorders, ALS, MS ... muscular atrophy, SLE ... Differential #Diagnosis #Algorithm
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Differential Diagnosis Algorithm ... Tumours - See ... Fractures #Pathologic #MSK ... Differential #Diagnosis #Algorithm
Shoulder Effusion Ballottement on Physical Examination

Shoulder effusion. You can ballot and see fluid return at posterior
can ballot and see ... #PhysicalExam #msk ... #orthopedics #clinical
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low complements ... lymphoproliferative syndrome Clinical ... RNP antibodies, Complement ... : Drug induced SLE
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Erythematosus Clinical ... anticoagulant • Complement ... Classification #Criteria #SLE