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diagnosis infections betadglucan galactomannan infectiousdiseases adrenal ai aspergillus biomarkers cancer comparison encephalopathy falsepositives hepatitis hepatology hypercalcemia hyponatremia injury insufficiency laboratory
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
for Concurrent ... Brain and Lung Infections ... Toxoplasmosis • Fungi ... #Concurrent #Differential ... #Diagnosis #causes
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... #Concurrent #Differential ... #Diagnosis #causes
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... ) • Fungi: Aspergillus ... #Concurrent #Differential ... #Diagnosis #causes
Causes of Encephalopathy - Differential Diagnosis Algorithm Hyperacute: - Primary Neurologic: Vascular (IS, ICH), Seizure, Migraine, Trauma
- Differential ... Diagnosis Algorithm ... Neoplasm-related (brain ... Inflammatory, Infectious (fungal ... #Causes
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - Differential ... Diagnosis Algorithm ... Solid Tumors: Lung ... #Diagnosis #Algorithm ... #causes #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal ... Insufficiency - Differential ... Diagnosis Algorithm ... , Disseminated Fungal ... #Causes #endocrinology
Lung Nodule - Differential Diagnosis Algorithm Nodule on > 2 Years Without a Change in Size: •
Lung Nodule - Differential ... Diagnosis Algorithm ... Infection: • Fungal ... #Nodule #Differential ... #Causes #Pulmonary
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... BAL GM does not differentiate ... decreased with: concurrent ... Clav (may be + as long
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
- Influenza A FUNGAL ... opsoclonus-myoclonus syndrome - brain ... - small cell lung ... Rhombencephalitis #Differential ... #Diagnosis #Causes
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... in BAL does not differentiate ... Sensitivity ↓ w/concurrent ... result in + as long
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