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diagnosis galactomannan candidemia fungemia laboratory microbiology sensitivity testing aspergillus biomarkers bloodcultures cglabrata characteristics comparison endocarditis falsepositives fungi fungus glabrata infective
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics 1,3 ß-D-glucan: • Most fungi excluding mucor and
Primarily studied for candida ... Glucan-containing gauzes ... @serotavirus #BetaDGlucan ... Specificity #Laboratory #InfectiousDiseases ... #Fungi #Fungal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... Polysaccharide cell wall component ... • Pathogens: Candida ... post-2010 almost never ... #Biomarkers #BetaDGlucan
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
• Cell wall component ... of many fungi ... • Routine use: Candida ... post-2010 almost never ... blood products #BetaDGlucan
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
Diagnosis and Management ... of complement components ... 2-6 months • Fever ... Weight Loss • Can cause ... #treatment #infectiousdiseases
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
therapy - Number one cause ... Fungal (Histoplasma ... patient a surgical candidate ... BloodCultures #Diagnosis #Management ... #Algorithm
Invasive Fungal Infection (IFI) Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
Common Pathogens Candida ... (most frequent cause ... and may include fever ... when feasible Management ... mortality #candida
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
COMMON CAUSES + ... negative bacteria, fungi ... (e.g., Candida) ... • Symptoms: Fever ... INITIAL MANAGEMENT
Candida Glabrata Species of Candida Most Commonly Isolated in Bloodstream Infections • Symptomatic mucosal infection is detected
infections include rare cases ... with persistent fever ... candidemia #diagnosis #management ... #fungemia #management ... #infectiousdiseases
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Nonspecific symptoms: Fever ... hearing loss, nausea ... connective tissue components ... ○ Syphilis ○ Fungal ... rheumatology #diagnosis #management
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